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  • Title: Chronic systemic (hepatosplenic) candidiasis in a patient with granulocytic sarcoma.
    Author: Gangadharan VP, Sasidharan K, Preetha S, Chithrathara K.
    Journal: Am J Clin Oncol; 2000 Dec; 23(6):562-3. PubMed ID: 11202796.
    Abstract:
    Chronic systemic (hepatosplenic) candidiasis (CSC) is a syndrome of invasive candidiasis characterized by fever without localizing signs or symptoms. It occurs predominantly in patients with acute leukemia, after prolonged severe neutropenia. We report a young woman who underwent extensive chemotherapy for granulocytic sarcoma of the ovary; CSC then developed in this patient. She was successfully treated with fluconazole and liposomal amphotericin B. Clinical presentation, diagnostic problems, and the current successful treatment with fluconazole and liposomal amphotericin B are discussed.
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