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  • Title: [Atenolol use in gestosis: clinical and hemodynamic aspects].
    Author: Shekhtman MM, Elokhina TB, Petrova SB, Sokolova MIu.
    Journal: Ter Arkh; 2000; 72(10):49-52. PubMed ID: 11220877.
    Abstract:
    AIM: To study clinical efficiency of atenolol in pregnancy hypertension with consideration of its cardiodynamic effects. MATERIAL AND METHODS: The trial included 36 women aged 19 to 41 years on pregnancy week 32 to 38. This study group had gestosis of the 1st and 2nd degree. Control group consisted of 14 healthy women with physiological pregnancy. All the examinees underwent atenolol test: measurement of heart rate, arterial pressure and ECG before, 30 and 90 min after introduction of a single atenolol dose 50 mg. Echo-CG was registered before and 90 min after administration of 50 mg amenolol, and on the treatment day 5. RESULTS: The response to atenolol in combined therapy of gestosis is the highest in gravidae with hyperkinetic type of circulation. CONCLUSION: Determination of the hemodynamic type is necessary for selection of antihypertensive drugs for treatment of gestosis.
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