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  • Title: Accumulation and depuration of paralytic shellfish poisoning toxins by purple clam Hiatula rostrata Lighttoot.
    Author: Chen CY, Chou HN.
    Journal: Toxicon; 2001 Jul; 39(7):1029-34. PubMed ID: 11223092.
    Abstract:
    Purple clams (Hiatula rostrata Lighttoot) accumulated paralytic shellfish poisoning (PSP) toxins produced by a toxic strain of the dinoflagellate Alexandrium minutum Halim for subsequent study of toxin distribution during depuration (detoxification by a nontoxic microalgal diet or starvation). The results confirm the data in the literature concerning the high toxicity of the digestive gland, and the depuration efficiency between feed with nontoxic microalgae and starvation is similar. The toxin profile of the purple clams was similar with that of Alexandrium minutum at the end of the exposure period; GTX4 and GTX1 were dominant. However, at the end of the depuration period, GTX3 and GTX2 were dominant. The non-visceral tissues were toxic after feeding with toxic algae. The toxicity was low and the profile were also similar with that of the toxic algae. No PSP toxins other than GTX-1, 2, 3 and 4 were detected in the experimental period.
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