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  • Title: Identification of a silent pituitary somatotropic adenoma based on a paradoxic response of growth hormone on a thyrotropin-releasing hormone or gonadotropin-releasing hormone provocation test.
    Author: Matsuno A, Ogino Y, Katayama H, Osamura RY, Nagashima T.
    Journal: Am J Obstet Gynecol; 2001 Feb; 184(3):286-8. PubMed ID: 11228475.
    Abstract:
    Preoperative endocrinologic identification and surgical removal of a silent somatotropic adenoma among patients with either amenorrhea or galactorrhea, or both, are beneficial for the restoration of menstruation and ovulation. Paradoxic rises of serum growth hormone in either a thyrotropin-releasing hormone or a gonadotropin-releasing hormone provocation test and high serum growth hormone levels were noted in the 3 patients with a silent somatotropic adenoma.
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