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  • Title: [Role of bronchospasm in development of bronchial obstruction in chronic bronchitis].
    Author: Nefedov VB, Shergina EA.
    Journal: Ter Arkh; 2000; 72(11):57-9. PubMed ID: 11229314.
    Abstract:
    AIM: To clarify the role of bronchospasm in impairment of bronchial permeability in chronic bronchitis. MATERIALS AND METHODS: Lung capacity (LC), forced lung capacity (FLC), forced expiration volume for 1 second (FEV1), FEV1/LC%, peak volume rate (PVS), maximal volume expiration rate (MVER) at the level of 25, 50 and 75% of LC were measured in 62 patients with chronic obstructive bronchitis before and after inhalation of 1 dose of berotec and 1 dose of atrovent. RESULTS: Bronchospasm was present in 42% of the patients, being the only cause of obstruction in 5% of patients. Other reasons added in 37%. Bronchospasm contribution to obstruction reached 21-40, 41-80, 81-100% in 5, 10 and 27% of patients, respectively. CONCLUSION: An important role of bronchospasm in development of bronchial obstruction in chronic bronchitis is proved.
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