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  • Title: Gastric signet ring cell adenocarcinoma metastatic to the iris.
    Author: Imamura Y, Suzuki M, Nakajima KI, Murata H.
    Journal: Am J Ophthalmol; 2001 Mar; 131(3):379-81. PubMed ID: 11239875.
    Abstract:
    PURPOSE: To report a case of gastric signet ring cell adenocarcinoma metastatic to the iris. METHODS: Case report. A 38-year-old man with a history of gastric signet ring cell adenocarcinoma presented with a white lacework-like mass on the iris of the left eye. RESULTS: Systemic medical evaluation demonstrated no other metastasis. Because of increased intraocular pressure, trabeculectomy and peripheral iridectomy were performed. Histology of the iris specimen demonstrated metastasis of gastric signet ring cell adenocarcinoma to the iris. CONCLUSION: Gastric signet ring cell carcinoma can metastasize to the iris. Ophthalmologists should include this possibility in the differential diagnosis when encountering a patient with a history of gastric adenocarcinoma and an iris mass.
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