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  • Title: Multiple aseptic pulmonary nodules with central necrosis in association with pyoderma gangrenosum.
    Author: Krüger S, Piroth W, Amo Takyi B, Breuer C, Schwarz ER.
    Journal: Chest; 2001 Mar; 119(3):977-8. PubMed ID: 11243990.
    Abstract:
    Pulmonary manifestations of pyoderma gangrenosum are relatively rare. We report the case of a 45-year-old patient with multiple pulmonary nodules with central necrosis as assessed by CT scan. The patient had a 4-year history of pyoderma gangrenosum with only minor skin manifestations. A CT-guided, fine-needle biopsy of the lung revealed a nonspecific, inflammatory, aseptic necrotic process, which was comparable to the skin biopsy of one pyoderma lesion. Following the initiation of oral prednisolone therapy, a rapid resolution of the pulmonary nodules occurred. We conclude that pulmonary nodules represent a rare pulmonary manifestation of pyoderma gangrenosum.
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