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  • Title: [The effect of partial hepatectomy on the quantity of somatotropes in rat adenohypophysis].
    Author: Sidorova VF.
    Journal: Biull Eksp Biol Med; 1975 Mar; 79(3):97-100. PubMed ID: 1125425.
    Abstract:
    Two thirds of the liver was removed by Higgins and Andersons method in which male rat weighing from 100 to 150 g. Adenohypophysis of partially hepatectomized, sham-operated and intact rats was studied 2, 4, 8-10, 25 hours, 2, 3, 6, 10, 14, 21 days after the operation. There was revealed a significant increase in the number of somatotropes 8-10 hours after the partial hepatectomy and a decrease in their content 25 hours after the operation, in comparison with their number in the smham-operated rats. The content of somatotropes in the adenohypophysis of the partially hepatectomized rats returned to the normal by the second postoperative day and failed to show any significant changes at the subsequent observation periods. The data obtained permit a supposition to be made on the participation of somatotropic hormone in the regulation of the restorative processes in the liver.
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