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  • Title: Genetics and molecular genetics of the MHC.
    Author: Rhodes DA, Trowsdale J.
    Journal: Rev Immunogenet; 1999; 1(1):21-31. PubMed ID: 11256569.
    Abstract:
    The MHC is a well-characterised region of the human genome, containing a high diversity of genes and an apparent clustering of genes involved in the immune response. The genomic sequence of an 8 Mb section, containing the MHC and flanking regions and covering over 300 genes, will soon be available. Since this is a highly polymorphic region, the molecular genetics of the MHC and its relationship with disease have been studied in considerable detail.
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