These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Study on the pathogenesis of free radical in nocturnal asthma].
    Author: Hamulati, Abuduaini, Abudureyimu.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 1998 Mar; 21(3):141-3. PubMed ID: 11263347.
    Abstract:
    OBJECTIVE: To examine the relationship between the pathogenesis of nocturnal asthma and free radicals. METHOD: The changes of the chemiluminescence of lymphocytes (Ly-cl) and polymorphonuclear leukocytes (PMN-cl) were studied by the cell chemiluminescence method. Glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) levels also were determined respectively. RESULT: The Ly-cl and PMN-cl in patients with nocturnal asthma on the second day 2:00 am were significantly higher than that of the second day 2:00 pm (P < 0.01) and higher than that of normal group (P < 0.01). The GSH-px were decreased and MDA were increased, and there were significant differences compared with normal group (P < 0.001, P < 0.01 respectively). CONCLUSION: There is an obvious difference on metabolism of free radicals on day and night in nocturnal asthma. The results support that the free radicals have an important role in pathogenesis of nocturnal asthma.
    [Abstract] [Full Text] [Related] [New Search]