These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: IgA and the IgA Fc receptor.
    Author: van Egmond M, Damen CA, van Spriel AB, Vidarsson G, van Garderen E, van de Winkel JG.
    Journal: Trends Immunol; 2001 Apr; 22(4):205-11. PubMed ID: 11274926.
    Abstract:
    IgA has traditionally been regarded a non-inflammatory antibody. This might indeed be true for secretory IgA (SIgA), which exerts its function at mucosal surfaces where commensal microorganisms and dietary antigens prevail. Serum IgA, however, potently triggers (pro)-inflammatory activity upon binding to the myeloid IgA receptor, FcalphaRI. Here, new insights in the roles of IgA and FcalphaRI are addressed and a model integrating the various functions of IgA in immunity is discussed.
    [Abstract] [Full Text] [Related] [New Search]