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  • Title: Fatal sepsis due to mycobacterium tuberculosis after allogeneic bone marrow transplantation.
    Author: Kindler T, Schindel C, Brass U, Fischer T.
    Journal: Bone Marrow Transplant; 2001 Jan; 27(2):217-8. PubMed ID: 11281394.
    Abstract:
    Mycobacterium tuberculosis is a serious, but rare infectious complication after allogeneic bone marrow transplantation. We describe a case of fatal sepsis due to Mycobacterium tuberculosis after allogeneic bone marrow transplantation for Philadelphia chromosome-positive ALL. The diagnosis was made after BAL. Although broad-spectrum antituberculous therapy was started immediately after diagnosis, blood cultures became positive for Mycobacterium tuberculosis. The patient developed severe pyrexias and finally died of multi-organ failure. Rapid progression of mycobacterial infection should be considered in patients post BMT with unexplained fever, particularly in patients from endemic areas.
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