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  • Title: Isolation of amantadine-resistant influenza a viruses (H3N2) from patients following administration of amantadine in Japan.
    Author: Iwahashi J, Tsuji K, Ishibashi T, Kajiwara J, Imamura Y, Mori R, Hara K, Kashiwagi T, Ohtsu Y, Hamada N, Maeda H, Toyoda M, Toyoda T.
    Journal: J Clin Microbiol; 2001 Apr; 39(4):1652-3. PubMed ID: 11283109.
    Abstract:
    In Japan, the use of amantadine for treatment of influenza A virus infection was not accepted until November 1998, although it was widely used for treatment of Parkinsonism. Since then, we have monitored the emergence of amantadine-resistant viruses and isolated two viruses from patients on long-term treatment with amantadine.
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