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  • Title: Amoebicidal and giardicidal compounds from the leaves of Zanthoxylum liebmannianun.
    Author: Arrieta J, Reyes B, Calzada F, Cedillo-Rivera R, Navarrete A.
    Journal: Fitoterapia; 2001 Mar; 72(3):295-7. PubMed ID: 11295310.
    Abstract:
    The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were isolated. Among them, asarinin was the most active with IC(50) values of 19.86 microg/ml for E. histolytica and 35.45 microg/ml for G. lamblia. The remaining compounds showed moderate activity against both parasites.
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