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  • Title: The effect of actinomycin D on estrogen-induced uterine blood flow.
    Author: Resnik R, Battaglia FC, Makowski EL, Meschia G.
    Journal: Am J Obstet Gynecol; 1975 Jun 01; 122(3):273-7. PubMed ID: 1130450.
    Abstract:
    The effect of actinomycin D on estrogen-induced uterine blood flow was studied in four nonpregnant, oophorectomized sheep, utilizing electromagnetic flow probes chronically implanted around the uterine arteris. Two hours after the intravenous injection of 1 mug of estradiol-17beta per kilogram of body weight, incorporation of [3H]-uridine into RNA was two- to threefold higher (2.7 plus or minus 0.4 S.E.M.) in the control horn than the uterine horn that had received an intra-arterial injection of actinomycin D. Actinomycin D had no effect on the estrogen-induced increase in uterine blood flow.
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