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  • Title: [Penicillin for acute throat infections. Are there arguments for modifying the guidelines of the Dutch College of General Practitioners?].
    Author: van den Bosch WJ.
    Journal: Ned Tijdschr Geneeskd; 2001 Mar 31; 145(13):612-3. PubMed ID: 11305208.
    Abstract:
    A recent study concludes that a 7-day penicillin treatment for a sore throat is superior to a 3-day treatment or a placebo, because the symptoms are resolved two days earlier. Prior to this study, the difference--based on the conclusions of a Cochrane review--was thought to be just 8 hours. The total number of patients included was too small to conclude that penicillin could reduce the number of short-term and long-term complications. In the guidelines of the Dutch College of General Practitioners, a 7-day penicillin treatment for a sore throat is only recommended in severe cases. It is still quite acceptable for Dutch GPs to discuss the treatment options for a sore throat with their patients. A change to the current guidelines is not necessary.
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