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  • Title: Successful management of polyneuropathy associated with IgM gammopathy of undetermined significance with antibody-based immunoadsorption.
    Author: Toepfer M, Schroeder M, Müller-Felber W, Lochmüller H, Sitter T, Pongratz D, Schiffl H.
    Journal: Clin Nephrol; 2000 May; 53(5):404-7. PubMed ID: 11305816.
    Abstract:
    Peripheral polyneuropathies associated with monoclonal IgM gammopathy of undetermined significance often have a progressive course and optimal treatment has not been established. We report on a patient diagnosed with polyneuropathy associated with benign IgM gammopathy, who was successfully treated with antibody-based immunoadsorption only. The neurological symptoms of the patient improved continuously over six months of treatment. Controlled trials should be performed to define this indication for antibody-based immunoadsorption therapy.
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