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  • Title: [Dopamine in essential arterial hypertension: excretion of its metabolite homovanillic acid].
    Author: Chávez Lara B, Serrano PA, Sánchez Torres G, Chávez Domínguez R.
    Journal: Arch Inst Cardiol Mex; 1975; 45(1):77-81. PubMed ID: 1130915.
    Abstract:
    The results obtained in a group of 66 hypertensive patients in which the AHV values were 5.7 plus and minus 0.4 mM/24 hrs., were reported. These values were compared to those obtained in 42 healthy subjects: 7.0 plus and minus 0.5 mM/24 hrs. The difference was statistically significant P less than 0.05. The values of excretion of urinary dopamine in both groups were also presented. A value of 225.7 plus and minus 13.0 mug/24 hrs. was obtained for the hypertensives, while the value for the healthy groups was 361.2 plus and minus 16.5. The statistical study in this case showed a high significance p smaller or less than 0.001. There were no changes in the levels of adrenaline and noradrenaline nor in the metabolite of these two amines, that is, AVM.
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