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  • Title: [Radioimmunological estimation of triiodothyronine in plasma. Diagnostic value in an area with endemic goitre (author's transl)].
    Author: Gehring D, Hoffman G, Thiele S, Ehret G.
    Journal: Dtsch Med Wochenschr; 1975 May 02; 100(18):996-1001. PubMed ID: 1132323.
    Abstract:
    In 896 patients from a low-iodine area the results of the radioimmununological triiodothyronine estimations in plasma were compared with the clinical and radioisotope findings of thyroid function. It was superior to the total thyroxine estimation (T4-test) in the differential diagnosis of hyperthyroidism. In euthyroid goitre the mean triiodothyronine concentration was significantly higher than in normal persons whereas the plasma thyroxine levels at the same time were significantly lower. Only in (primary) hypothyroidism is the triiodothyronine estimation diagnostically less important than the T4-test. In summary, the radioimmunochemical method permits a clearly more precise evaluation of thyroid function even in areas of endemic goitre.
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