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  • Title: [Clinical significance of changes of interleukin 6 level in pregnancy induced hypertension].
    Author: Wang Z, Song H, Shi S.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 1999 Apr; 34(4):220-1. PubMed ID: 11326919.
    Abstract:
    OBJECTIVE: To assess the clinical significance of changes of interleukin-6 (IL-6) level in patients with pregnancy induced hypertension (PIH). METHODS: IL-6 level in urine and blood were measured by sandwich enzyme labeled immunosorbent assay (ELISA) in 82 patients with PIH and 30 normal pregnant women. RESULTS: Blood IL-6 level in severe PIH patients was significantly higher than that in mild PIH patients and normal pregnant women. IL-6 level of urine in PIH patients were significantly higher than that in normal pregnant women and was associated with the severity of disease. There was a positive correlation between urinary IL-6 level and severity of renal damage in PIH. CONCLUSION: Determination of IL-6 level is useful to understand the severity of PIH and its renal damage.
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