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  • Title: Could platelet activating factor play a role in developmental dyslexia?
    Author: Taylor KE, Richardson AJ, Stein JF.
    Journal: Prostaglandins Leukot Essent Fatty Acids; 2001 Mar; 64(3):173-80. PubMed ID: 11334553.
    Abstract:
    Post-mortem studies by Galaburda and colleagues on the brains of developmental dyslexics found characteristic neuronal abnormalities: ectopias, microgyria, and fewer large-soma cells in sensory thalamus. An association between dyslexia and immune dysfunction has also been proposed. We describe a mechanism which may explain these observations. Platelet-activating factor (PAF) is a pro-inflammatory lipid implicated in neurological disorders. We propose that PAF may also be involved in dyslexia.
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