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  • Title: [Postinfarction remodeling of the left atrium and left ventricle: effects of long-term treatment with beta adrenergic blockers and angiotensin converting enzyme inhibitors].
    Author: Mazur NA, Vikent'ev VV.
    Journal: Ter Arkh; 2001; 73(2):29-32. PubMed ID: 11338850.
    Abstract:
    AIM: To study changes in left atrial volume, geometry and function in myocardial infarction (MI) patients treated with beta-adrenoblocker and ACE inhibitor. MATERIAL AND METHODS: 65 patients with Q-wave myocardial infarction (MI) were followed up for 6 months. Regular check-ups included clinical examination, ECG, echo-CG, dopplercardiography. RESULTS: In MI patients left ventricular remodeling is associated with left atrial remodeling. The greatest inhibition of remodeling in patients with symptoms of cardiac failure was reached with captopril therapy. Atenolol in this respect is less effective. If cardiac failure in MI patients is absent, atenolol impact on the remodeling is stronger than that of captopril. CONCLUSION: In postmyocardial infarction patients remodeling occurs in both heart chambers. The presence of cardiac failure affects remodeling inhibition rate, especially under treatment with beta-adrenoblocker.
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