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  • Title: Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica.
    Author: Naidu D, Ragsdale SW.
    Journal: J Bacteriol; 2001 Jun; 183(11):3276-81. PubMed ID: 11344134.
    Abstract:
    The Moorella thermoacetica aromatic O-demethylase was characterized as an inducible three-component system with similarity to the methanogenic methanol, methylamine, and methanethiol methyltransferases and to the O-demethylase system from Acetobacterium dehalogenans. MtvB catalyzes methyl transfer from a phenylmethylether to the cobalt center of MtvC, a corrinoid protein. MtvA catalyzes transmethylation from MtvC to tetrahydrofolate, forming methyltetrahydrofolate. Cobalamin can substitute for MtvC.
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