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  • Title: Pentagastrin increases phenylalanine and decreases histidine incorporation to proteins of rat stomach.
    Author: Evans DC, Lin TM.
    Journal: Res Commun Chem Pathol Pharmacol; 1975 Mar; 10(3):597-600. PubMed ID: 1135525.
    Abstract:
    Female rats were treated with L-phenylalanine-14C or L-histidine-14C, 20 mug/kg i.p. one hour before receiving pentagastrin 250 mug/kg s.c. Sixty minutes after injection of pentagastrin the incorporation of L-phenylalanine-14C into the proteins of the squamous and fundic portions of the stomach was significantly increased respectively by 18 and 17.5%. On the contrary, the uptake of Lhistidine-14C into the proteins of the squamous (-24%), fundic (-18% and duodenal (-16%) regions was significantly decreased. Incorporation of histidine and phenylalanine into the proteins of the pylorus was not significantly affected by pentagastrin.
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