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  • Title: Thymic hyperplasia in a patient with Graves' disease.
    Author: Hsu LH, Chen JC, Tsai GJ, Tsou MH, Hsu WH.
    Journal: Zhonghua Yi Xue Za Zhi (Taipei); 2001 Feb; 64(2):115-20. PubMed ID: 11355328.
    Abstract:
    Hyperplastic changes of the thymus may be found in patients with Graves' disease. However, this rarely presents as an anterior mediastinal mass, particularly among adults. In this report, we describe a 32-year old woman with Graves' disease and hyperthyroidism. During medical evaluation and treatment for her hyperthyroidism, a large anterior mediastinal mass was incidentally discovered. A cytological study of the lesion via computed tomogram-guided fine needle biopsy could not make a definitive diagnosis and suggested the possibility of a thymoma, which led to a surgical exploration. However, the final pathological diagnosis of the surgically removed tissue was thymic hyperplasia. The relationship between Graves' disease and thymic changes is discussed.
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