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Title: FDA approves new PCP drug. Food and Drug Administration. Journal: AIDS Alert; 1995 Aug; 10(8):108. PubMed ID: 11362680. Abstract: The U.S. Food and Drug Administration (FDA) recently approved a suspension formulation of atovaquone (Mepron) for treating mild to moderate cases of pneumocystis carinii pneumonia (PCP) in patients intolerant of trimethoprim/sulfamethoxazole (TMP-SMX). The liquid form offers better bioavailability and convenient dosing. At least one study has shown that the drug is less toxic than intravenous pentamidine and may have possible action against microsporidiosis. The use of the suspension formulation for chronic preventive therapy against PCP also is being studied.[Abstract] [Full Text] [Related] [New Search]