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Title: PHS guidelines map out prevention routes through terrain of infections. Public Health Service. Journal: AIDS Alert; 1995 Sep; 10(9):109-11. PubMed ID: 11362773. Abstract: Interaction between health agencies, community groups, AIDS patients, and the U.S Public Health Service has finally resulted in the creation of the first comprehensive guide for preventing AIDS-related opportunistic infections. Hundreds of drug studies were sorted through to assess which drugs prevented opportunistic infections the best. Other suggestions in the guidelines involved quality-of-life decisions, such as owning pets and drinking tap water. The top priorities in the guidelines were prevention of Pneumocystis carinii pneumonia, toxoplasmosis, and tuberculosis, while preventive therapy of Mycobacterium avium disease was given a lower priority. The guidelines did not recommend ganciclovir or acyclovir prophylaxis for cytomegalovirus disease, nor did they recommend prophylaxis for fungal infections because the development of resistance to the drugs may make them ineffective when their use is more crucial. Insurance considerations were also considered when developing the guidelines.[Abstract] [Full Text] [Related] [New Search]