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Title: New trials reach same conclusion: two drugs are better than AZT alone. Journal: AIDS Alert; 1995 Nov; 10(11):133-6. PubMed ID: 11362921. Abstract: Two large trials, ACTG 175 and Delta, are showing that long-term monotherapy for HIV infection is outdated. Long-term monotherapy with AZT, recommended since 1993, is no longer defensible. ACTG 175 confirms the emerging theme of other studies, suggesting that the drug's efficacy is limited to one or two years. Options of what to switch to or what to add will be determined on an individual basis. The National Institute of Allergy and Infectious Diseases (NIAID) is expected to change treatment standards for antiretrovirals after the CPCRA 007 trial data is included.[Abstract] [Full Text] [Related] [New Search]