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  • Title: 3TC/AZT: just another combination.
    Journal: GMHC Treat Issues; 1995 Dec; 9(12):2. PubMed ID: 11362997.
    Abstract:
    The Food and Drug Administration (FDA) has granted approval for the use of 3TC (Epivir) in combination with AZT for any stage of HIV. Of all the available nucleoside analog combinations, 3TC/AZT is considered the best. Although research has shown that CD4 cell counts receive approximately the same boost from 3TC/AZT and ddI/AZT, HIV does not appear to be resistant to 3TC and AZT simultaneously. However, an analysis of drug resistance in the North American AZT-experienced 3TC study found that dual resistance does occur.
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