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  • Title: CMV news.
    Journal: Posit Aware; 1996; 7(1):5-6. PubMed ID: 11363124.
    Abstract:
    The Food and Drug Administration (FDA) approved oral ganciclovir as the first preventive treatment for cytomegalovirus (CMV) in people with advanced stages of AIDS. CMV and its most common manifestation, CMV retinitis, affect 25 to 40 percent of AIDS patients and can lead to blindness. Hoffmann-La Roche will offer a screening program for CMV retinitis to 200 AIDS health organizations and clinics. A video, a brochure, and an Amsler grid which allows patients to check for blind spots and distortions at home will be available through the program. A published study found that the inhibition of CMV replication also inhibits HIV through a lowering of p24 antigen, an HIV protein. Ganciclovir and foscarnet, used as CMV treatments, were found to equally lower the p24 antigen.
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