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  • Title: Detecting CMV retinitis: know what to look for. Treatment is effective but not pleasant.
    Journal: AIDS Alert; 1996 Mar; 11(3):suppl 1-2. PubMed ID: 11363248.
    Abstract:
    Approximately one-third of all AIDS patients develop cytomegalovirus (CMV) retinitis. Symptoms begin with blurred vision, loss of peripheral vision, and dark spots in the eye that obstruct vision. HIV-infected persons with CD4 counts below 100 should be tested twice a year for CMV. Oral ganciclovir (Cytovene) is a preventive option approved by the Food and Drug Administration (FDA). If diagnosed with CMV, a regimen of the antiviral drugs foscarnet and ganciclovir is initiated either as monotherapy or in combination. Side effects of combination therapy are greater than monotherapy and the treatment takes longer. Direct ganciclovir injections into the eye and ganciclovir implants are other options but are not FDA-approved. Other eye diseases can also occur, such as tumors, infections, and neuro-ophthalmic disorders.
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