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Pubmed for Handhelds

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  • Title: A more practical therapy for low platelets.
    Author: Torres G.
    Journal: GMHC Treat Issues; 1996 Jan; 10(1):9-10. PubMed ID: 11363379.
    Abstract:
    The Food and Drug Administration (FDA) approved WinRho as a new treatment for ITP or thrombocytopenic purpura (low blood platelet count) in people with HIV. Current treatment options for ITP include AZT, corticosteroids, immunoglobulin therapy, and splenectomy. Clinical evaluation rates AZT as the best of the options. WinRho treatment will not work on Rh-negative patients or patients with no spleen. The largest WinRho study to date, involving 267 patients, shows a mean platelet increase of 76,000 cells with no adverse effect on CD4 counts or evidence of an acceleration of HIV disease progression. HIV-positive patients had a poorer platelet increase response than HIV-negative patients.
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