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  • Title: Ritonavir/saquinavir trial announced.
    Journal: J Int Assoc Physicians AIDS Care; 1996 Apr; 2(4):59. PubMed ID: 11363522.
    Abstract:
    Interest in using ritonavir and saquinavir for combination therapy is high, but the safety of this combination has not been established. Abbott Laboratories released details of a combination therapy trial anticipated to begin in mid-April 1996. One hundred twenty HIV-infected patients will be sequentially tested using four dose combinations. There are concerns that incorrect dose combinations will create dangerous drug levels previously untested in man or will result in suboptimal antiviral efficacy and decreased future response to protease inhibitor therapy.
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