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  • Title: Non-nucleoside reverse transcriptase inhibitors.
    Author: Bowers M.
    Journal: BETA; 1996 Jun; ():19-22. PubMed ID: 11363645.
    Abstract:
    The Food and Drug Administration (FDA) approved antiretroviral drugs for HIV treatment from 3 classes: nucleoside analog reverse transcriptors, protease inhibitors, and non-nucleoside reverse transcriptase inhibitors (NNRTI). NNRTI drugs target the same enzyme as the nucleoside analog drugs, but interfere in a different manner. Clinical data on nevirapine, delavirdine, and loviride are presented; other drugs are currently under development. Resistance and combination therapy issues are discussed.
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