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Title: Still looking for the real GEM. Journal: GMHC Treat Issues; 1996 Apr; 10(4):9. PubMed ID: 11363711. Abstract: Excitement caused by reports of the GEM 91, the first antisense drug to be used against HIV, has been dampened by results of clinical trials. GEM 91 is broken down in the body too quickly for it to reach effective concentrations. New formulations are being developed that will hopefully work better. A phase I AZT/GEM 91 interaction trial using a new formulation is planned.[Abstract] [Full Text] [Related] [New Search]