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  • Title: ddI plus d4T.
    Author: James JS.
    Journal: AIDS Treat News; 1996 Sep 06; (No 254):4. PubMed ID: 11363818.
    Abstract:
    A study of 85 volunteers divided into 5 separate dosage groups found fairly good viral suppression from a combination of didanosine plus stavudine. A 1.3 log viral load reduction was sustained for at least 52 weeks when the 5 dose groups were pooled together. For the individual groups, reductions were 1.1 to 1.8 logs at 52 weeks. By the eighth week, average CD4 count increased by about 80, and this increase was sustained until at least week 52. Treatment was well tolerated with no dose-related adverse events.
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