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  • Title: A patient's guide to protease inhibitors.
    Author: Elperin A, Sax P.
    Journal: AIDS Clin Care; 1996 Oct; 8(10):83-4. PubMed ID: 11363988.
    Abstract:
    Dosage guidelines and side effects of three currently available protease inhibitors (saquinavir, ritonavir, indinavir) reveal very different patterns. Dosage regimens are as follows: saquinavir, 3 capsules every 8 hours with food; ritonavir, 6 capsules every 12 hours with food; and indinavir, 2 capsules every 8 hours on an empty stomach. Ritonavir has the severest side effects, including nausea, diarrhea, and initially, tingling feeling of the mouth, arms, or legs. The drugs work best when taken with well-studied medicines such as AZT, d4T, and ddI.
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