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  • Title: Protease inhibitors linked to drop in CMV retinitis.
    Journal: AIDS Alert; 1997 Aug; 12(8):92-4. PubMed ID: 11364475.
    Abstract:
    Several studies suggest that protease inhibitor therapy is linked with a decrease in cases of cytomegalovirus (CMV) retinitis, as high as 50 percent at one institute. CMV retinitis afflicts about 40 percent of AIDS patients, and current treatment is intermittent intravenous ganciclovir, which can cause severe liver toxicity. The incidence of CMV retinitis is also related to CD4 counts, but clinicians are warned that rising CD4 counts do not necessarily mean that their patients are no longer at risk for developing CMV retinitis.
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