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  • Title: Delavirdine levels in women.
    Author: Vazquez E.
    Journal: Posit Aware; 1997; 8(4):14. PubMed ID: 11364481.
    Abstract:
    Results from a clinical trial of 718 participants, 139 of them women, indicate that women experience 1.8 times higher concentrations of delavirdine (Rescriptor) than do men. Women's smaller body size increases the dose per kilogram ratio compared to men, although pharmacokinetic studies have not demonstrated a gender difference in metabolism. The main side effect caused by delavirdine, a non-nucleoside reverse transcriptase inhibitor produced by Pharmacia and Upjohn, is a temporary rash that disappears without changing the treatment.
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