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  • Title: HIV research overview: interview with David Ho, M.D. Interview by John S. James.
    Author: Ho D.
    Journal: AIDS Treat News; 1997 Nov 07; (No 282):1-6. PubMed ID: 11364903.
    Abstract:
    In an interview with AIDS Treatment News, Dr. David Ho, director of the Aaron Diamond AIDS Research Center, provides his views on current HIV treatment research. Dr. Ho discusses 1) research on early and aggressive treatment, 2) the practice of individualizing drug doses based on frequent blood monitoring to retard drug resistance and viral rebound, 3) recent reports of triple combination therapy virological failure with CD4 counts remaining high and viral load not rebounding as high, 4) the necessity for viral load testing to measure fewer than 400 copies, 5) the role of viral resistance testing for drug selection, and 6) whether complete viral eradication is possible. Dr. Ho states that although it is rare, a person can become reinfected with a second strain of HIV once one strain has been established. In the future, there will be better and less toxic drugs and possibly eradication.
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