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  • Title: New formulation of saquinavir (Fortovase) is more effective.
    Author: Tam CW.
    Journal: Fac Notes (New Orleans La); 1998; 10(2):11. PubMed ID: 11365126.
    Abstract:
    The Food and Drug Administration (FDA) recently approved a new soft gel capsule formulation of saquinavir (Fortovase). Fortovase, manufactured by Hoffmann-LaRoche, has the same active ingredient as Invirase (saquinavir mesylate); however, the drugs cannot be used interchangeably. The approval was based on studies showing significant viral load reductions when used with two nucleoside analogues, and the drug is more readily absorbed than the non-gel version. Factors for considering converting patients to this drug are listed, along with known adverse effects and potential drug interactions.
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