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Title: ACTG 343: (why) we can't relax our grip on viral suppression. Author: Maenza JR. Journal: Hopkins HIV Rep; 1998 May; 10(3):10. PubMed ID: 11365491. Abstract: An AIDS Clinical Trials Group study examined whether less intensive maintenance antiretroviral regimens could be effective after the initial use of highly active induction therapy. Results from 309 patients, who were evaluated in the maintenance phase, demonstrated that 6 months of therapy with AZT/3TC/IDV, followed by less intensive treatment, is not an effective strategy. Results suggest that once viral suppression has been achieved, intensity of therapy should not be lessened.[Abstract] [Full Text] [Related] [New Search]