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  • Title: Short course preventive therapy for tuberculosis is successful in HIV-infected patients.
    Author: Chaisson RE.
    Journal: Hopkins HIV Rep; 1998 May; 10(3):2-3. PubMed ID: 11365493.
    Abstract:
    Two independent clinical trials are showing that patients with HIV and latent tuberculosis infections may only need two months of treatment to prevent active tuberculosis development. Studies examined the use of rifampin (RIF) and pyrazinamide (PZA), or isoniazid (INH) and pyridoxine. Results show that RIF/PZA, dosed either daily or twice weekly, is as effective in preventing tuberculosis in dually-infected adults, as INH/pyridoxine given for 6-12 months. Data on drug regimens used in preventing tuberculosis in patients with HIV infection are highlighted.
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