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Title: Controversial HIV vaccine enters phase III trials amid skepticism. Journal: AIDS Alert; 1998 Dec; 13(12):133-4, 136. PubMed ID: 11366059. Abstract: Clinics have begun enrolling volunteers in the first phase III trial of an HIV vaccine. Developing the vaccine has been a goal for nearly two decades, but leading scientists are skeptical about the effectiveness of a vaccine which does not use live viruses. More than 34 different candidate vaccines have been tested in phase I, and three are in phase II. The vaccine, AIDSVAX, is designed to train the immune system to protect itself against infection by creating antibodies. The scientific and political issues associated with the vaccine are presented.[Abstract] [Full Text] [Related] [New Search]