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  • Title: Study offers hope for Africa's next generation.
    Journal: WORLD; 1999 Sep; (No 101):4-5. PubMed ID: 11366948.
    Abstract:
    Every day about 1,800 babies are born infected with HIV in developing countries. According to UNAIDS estimates, the antiretroviral Nevirapine (NVP or Viramune) may reduce the transmission rate of HIV from a mother to her child. According to a joint Uganda-U.S. study (HIVNET 012), a single oral dose of Nevirapine, given to an HIV-infected woman during labor, and a single dose given to her baby within 3 days of birth reduces the HIV transmission rate from mother to baby by half compared to AZT. This intervention could prevent 300,000 to 400,000 newborns from being born infected with HIV each year, at a cost of $4 per delivery. The impact of breast-feeding on HIV transmission, the implications of HIVNET 012 on treatment in the U.S., and other studies that have addressed mother-to-child HIV transmission are also addressed.
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