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  • Title: Stopping preventive treatments.
    Author: Fornataro K, Jefferys R.
    Journal: Body Posit; 1999 Jul; 12(7):9-10. PubMed ID: 11367080.
    Abstract:
    Although combination therapy with HAART (Highly Active AntiRetroviral Therapy) can increase CD4 (T-cell) counts, doctors have been cautious about stopping preventive treatments, or prophylaxis, for PCP (Pneumocystis carinii pneumonitis). Two studies, however, suggest that if HAART increases T-cell counts to over 200 for an extended time period, PCP prophylaxis may be safely stopped. Partly as a result of these study findings, the United States Public Health Service has rewritten guidelines on the prevention of opportunistic infections. The draft version continues to call for PCP prevention beginning when patients have T-cell counts below 200 or have a history of thrush. However, a new section states that providers may stop prophylactic treatment when T-cell counts remain over 200 for at least three to six months. Recommendations for preventing MAC (mycobacterium avium complex) and CMV (cytomegalovirus) have also changed with HAART and are briefly described.
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