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  • Title: Mother-to-child HIV prevention: is elective C-section necessary?
    Journal: Proj Inf Perspect; 1999 Sep; (28):19. PubMed ID: 11367360.
    Abstract:
    Studies have shown that the use of AZT (Retrovir) during pregnancy and delivery by Cesarean-section (abdominal surgical delivery, also known as C-section) used before labor starts (elective C-section) can reduce the risk of mother-to-child HIV transmission (vertical transmission). Other studies are underway to determine if combination therapy can further reduce the rate of vertical transmission. Though delivery by C-section can reduce the risk of vertical transmission, it can also cause complications such as hemorrhage (uncontrolled bleeding), infection, and death. Also discussed is the need for more studies on the effects of triple-drug therapy and maternal viral load on vertical transmission as well as the relationship between HIV infection and post-operative complications. In addition, the concerns of drug treatment of fungal infections during pregnancy are presented in a side panel.
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