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  • Title: [Comparative study on the effect of gossypol and T7 on human spermatozoa ATPase activity].
    Author: Wu F, Zhang Z, Ye W, Qian X.
    Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 1998 Aug; 20(4):267-70. PubMed ID: 11367690.
    Abstract:
    OBJECTIVE: A comparative study was carried out on the effect of two kinds of male contraceptive drugs, gossypol and the abstract of tripterygium wilfordii T7, on the human spermatozoa ATPase activity. METHODS: The specific activity of total ATPase and Na-K ATPase of spermatozoa was assayed in this experiment. RESULTS: (1) The effect of gossypol on the human spermatozoa ATPase activity is inhibitory and concentration-dependent; and (2) The abstract of tripterygium wilfodii T7 has no effect on the human spermatozoa ATPase activity. CONCLUSIONS: The antifertility effects of gossypol and T7 are different.
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