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  • Title: [Non-small cell lung cancer with liver metastasis responsive to gemcitabine--a case report].
    Author: Sakurai T, Oura S, Yoshimasu T, Tanino H, Kokawa Y, Nakamura T, Matsuyama K, Naito Y.
    Journal: Gan To Kagaku Ryoho; 2001 May; 28(5):707-10. PubMed ID: 11383223.
    Abstract:
    A 56-year-old male patient underwent a right upper lobectomy and lymph node dissection for non-small cell lung cancer in March 1994. Multiple lung metastases in the right lung were found 45 months after the operation, and chemotherapy with docetaxel was administered. A liver metastasis was detected 11 months later, and it was refractory to docetaxel. Therefore, the patient was treated with cisplatin, mitomycin C and vinorelbine, which resulted in no change to the liver metastasis. He was next treated with gemcitabine, which resulted in a partial response of the liver metastasis. The adverse effects of gemcitabine were Grade 3 thrombocytopenia and Grade 2 neutropenia. The response duration for gemcitabine therapy was three months.
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