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  • Title: An investigation in man into the relative potency of lignocaine, bupivacaine and etidocaine.
    Author: Morgan M, Russell WJ.
    Journal: Br J Anaesth; 1975 May; 47(5):586-91. PubMed ID: 1138776.
    Abstract:
    The relative potency of lignocaine, bupivacaine and etidocaine was estimated by forearm skin weals in four volunteers. Potency was estimated as the time to half-recovery of a sharp sensation in response to a needle-prick. The increase in duration of action with increased concentration was greater for bupivacaine and etidocaine as compared with lignocaine. At the same concentrations, bupivacaine had a longer duration of action than etidocaine. However, etidocaine 1% had a longer duration of action than bupivacaine 0.5%.
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